
Complete confocal fluorescence microscope that empowers researchers to advance quantitative functional imaging from individual molecules to cells and tissues.

Modular, customizable, time-resolved confocal microscope with single-molecule sensitivity for life and materials science.

Compact FLIM and FCS upgrade kit that adds advanced functional imaging and correlation analysis to existing laser scanning microscopes.

Designed for flexible, sensitive, and precise steady-state and time-resolved spectroscopy across the UV to NIR range and time scales from picoseconds to milliseconds.

Modular lifetime spectrometer designed for flexible fluorescence and photoluminescence measurements in both materials and life science research.

Add spectral and time-resolved photoluminescence to your setup through flexible microscope–spectrometer coupling options.

Get the most out of superconducting nanowire detectors in large-scale quantum communication and computing experiments requiring precise multichannel timing.

Boost your time-resolved experiments with a flexible, high-precision time tagging and TCSPC unit for materials science and quantum sensing.

Scale your photonic quantum computing and detector characterization setups while maintaining performance, flexibility, and high data throughput.

Compact 3-color picosecond laser delivering flexible ns to ms excitation with cost-effective multicolor performance and straightforward operation.

Smart picosecond laser diode heads covering UV-A to NIR, providing the right combination of power, pulse width, and diode type for any time-resolved technique.

VisUV provides clean short pulses and stable timing across key UV and visible wavelengths, including deep UV lines as well as 488 nm and 532 nm.

Enhance your single-photon counting experiments with wide dynamic range and excellent timing precision in the UV and visible even at the highest count rates.

Capture even the weakest signals over large areas with maximum dynamic range and enhanced low-light sensitivity in a compact detector design.

Unlock spatially resolved single-photon detection with a 23-pixel SPAD array, combining low dark counts and precise time tagging for advanced experiments.

Advanced FLIM analysis software for fast, accurate interpretation of lifetime imaging data.

Intuitive, free software solution for real-time, high-precision photon data acquisition, visualization, and initial data analysis.

Advanced software for time-resolved fluorescence acquisition and analysis.

An imaging technique that uses fluorescence lifetimes to generate image contrast.

Investigating how proteins dynamically explore multiple conformational states that control biological function.

Investigating how biomolecules separate into dynamic liquid phases to organize cellular space and regulate biological function.

A time-resolved technique that measures photoluminescence lifetimes to reveal excited-state dynamics in materials.

Studying exciton dynamics, charge carrier processes, and structural properties through optical and time-resolved characterization methods.

Investigating charge-carrier lifetimes and recombination dynamics to enable precise optical characterization of material quality and device performance.

A quantum optical signature revealed by time-resolved photon correlation analysis to identify single-photon emission in materials and nanostructures.

The transmission of information using individual photons, using quantum effects to ensure absolute security.

Quantifying photons per detection event enables direct access to photon-number statistics, providing insight into quantum and statistical properties of light.

An optical technique that analyzes light emission under electrical excitation to reveal electronic properties of electroluminescent materials.

Monitoring environmental signals and trace compounds to understand dynamic changes in natural and engineered environments.

A photon timing technique that measures single-photon arrival times to resolve ultrafast dynamics in fluorescence, materials research, and quantum optics.
TimeHarp 260 is a compact, PCIe-based time tagging and TCSPC card designed for straightforward system integration and reliable photon-counting performance. Based on a custom TDC architecture, it delivers precise picosecond timing with ultrashort dead time and supports high-throughput operation. Available in PICO and NANO versions as well as SINGLE and DUAL configurations, TimeHarp 260 offers flexible performance as well as detector and synchronization channel options.
TimeHarp 260 addresses OEM and seamless system-integration scenarios across all disciplines as well as entry-level and educational photon-counting applications. It provides a practical platform for learning, prototyping, and deploying time-resolved measurement techniques where reliable picosecond timing and tight system integration are required. Engineered for long-term reliability and seamless integration, TimeHarp 260 comes with a 5-year warranty.
| TimeHarp 260 PICO | TimeHarp 260 NANO | |
| Number of detector channels (in addition to sync) | 1 (SINGLE) or 2 (DUAL) | 1 (SINGLE) or 2 (DUAL) |
| Input voltage range (pulse peak into 50 Ohms) | 0 to - 1200 mV, optimum: - 100 mV to - 200 mV | - 1200 mV to + 1200 mV |
| Input voltage max. range (damage level) | ± 1500 mV | ± 2500 mV |
| Trigger method | Falling edge | Falling or rising edge, software adjustable |
| TimeHarp 260 PICO | TimeHarp 260 NANO | |
| Minimum time bin width | 25 ps; in optional "long range mode": 2.5 ns | 250 ps* |
| Timing precision** | < 20 ps RMS; in optional "long range mode": < 1 ns RMS | < 250 ps RMS* |
| Timing precision / √2** | < 14 ps RMS; in optional "long range mode": < 710 ps RMS | < 180 ps RMS* |
| Dead time | < 25 ns; in optional "long range mode": < 2.5 ns | < 2 ns |
| Differential non-linearity | < 2 % peak; < 0.2 % RMS (over full measurement range) | < 2 % peak; < 0.2 % RMS (over full measurement range) |
| Maximum sync rate (periodic pulse train) | 100 MHz | 100 MHz |
| TimeHarp 260 PICO | TimeHarp 260 NANO | |
| Count depth | 32 bit (4 294 967 296 counts) | 32 bit (4 294 967 296 counts) |
| Maximum number of time bins | 32 768 | 32 768 |
| TimeHarp 260 PICO | TimeHarp 260 NANO | |
| Sustained throughput (sum of all channels)*** | 40 Mcps | 40 Mcps |
| TimeHarp 260 PICO | TimeHarp 260 NANO | |
| Period | Programmable, 0.1 µs to 1678 s (0.596 Hz to 10 MHz) | Programmable, 0.1 µs to 1678 s (0.596 Hz to 10 MHz) |
| TimeHarp 260 PICO | TimeHarp 260 NANO | |
| Number | 4 (only available in DUAL models with 2 detection channels) | 4 (only available in DUAL models with 2 detection channels) |
* applies to TimeHarp 260 Nano with base resolution = 250 ps (shipped after 2015). Earlier boards have a resolution of 1 ns but can be returned for an upgrade to 250 ps upon request.
** In order to determine the timing precision it is necessary to repeatedly measure a time difference and to calculate the standard deviation (RMSerror) of these measurements. This is done by splitting an electrical signal from a pulse generator and feeding the two signals each to a separate input channel. The differences of the measured pulse arrival times are calculated along with the corresponding standard deviation. This latter value is the RMS jitter which we use to specify the timing precision. However, calculating such a time difference requires two time measurements. Therefore, following from error propagation laws, the single channel RMS error is obtained by dividing the previously calculated standard deviation by √2. We also specify this single channel RMS error here for comparison with other products.
*** Sustained throughput depends on configuration and performance of host PC
**** AMD processor chips recommended
All Information given here is reliable to our best knowledge. However, no responsibility is assumed for possible inaccuracies or omissions. Specifications and external appearances are subject to change without notice.
Contains specifications, features and applications of the TCSPC and MCS PCIe board offering high timing resolution and time tagging
Coveres measurement principles, instrumentation, TCSPC detection, and applications in materials and life sciences
Explore how advanced time tagging, correlation analysis, and high-speed TCSPC electronics enable precise photon-counting measurements across a wide range of scientific applications.

Time-Tagged Time-Resolved (TTTR) mode records every photon event with its exact arrival time and channel assignment, enabling detailed offline analysis of fluorescence dynamics, correlation processes, and single-molecule behavior. It supports applications ranging from FCS and burst analysis to fast FLIM and quantum optics. Both T2 and T3 modes are available, covering free-running timing across all inputs. Dual-channel versions can also capture external marker events for precise synchronization with scanners and other hardware. Learn more about TTTR in our blog article.

TimeHarp 260 is built on a custom time-to-digital converter (TDC) architecture developed using fast SiGe technology, enabling picosecond timing, ultrashort dead time, and high sustained count rates. The poster “High Speed Multichannel TCSPC Electronics” provides an in-depth look at the underlying hardware design, including the multichannel TDC layout, FPGA-based data processing pipeline, and the memory-efficient event handling used for time tagging and correlation measurements. It also highlights the Long Range Mode, which extends the measurable time window for phosphorescence and long-lived decay processes into the second range while maintaining excellent timing performance. Test data, correlation measurements, and FLIM examples illustrate the robustness and precision of the electronics across a wide range of photon-counting applications.

Coincidence correlation measurements on a picosecond timing scale are a powerful tool in life sciences and quantum optics. In quantum optics, they are used to investigate phenomena such as photon antibunching, quantum entanglement, and single-photon emission. By correlating photon arrival times from multiple detectors, it becomes possible to determine whether an emitter behaves as a true single-photon source. The example shown demonstrates antibunching from nitrogen vacancy (NV) centers in nanodiamonds, confirming the presence of a single quantum emitter.
TimeHarp 260 is supported by intuitive acquisition software for fast setup, live monitoring, and clear data visualization, while flexible programming interfaces enable custom automation and experiment control. From ready-to-use GUI operation with UniHarp to scripting and integration via Python, C/C++, LabVIEW, and MATLAB using snAPI and programming libraries, the platform adapts seamlessly to both routine measurements and advanced, application-specific workflows.

UniHarp is PicoQuant’s free data acquisition software for TCSPC and time-tagging devices, offering real-time control, clean visualization, and flexible data saving. It supports time traces, histograms, correlation measurements (including g² and FCS), and provides an easy, intuitive workflow for configuring and running experiments.

snAPI is PicoQuant’s efficient Python interface for TCSPC hardware, enabling streamlined device communication, configuration, and data handling. It allows users to build custom scripts, automation routines, and analysis pipelines with minimal overhead.
This application note demonstrates high-speed protein lifetime measurements using a 280 nm picosecond laser for sensitive time-resolved fluorescence spectroscopy.
Application note on rapidFLIM HiRes for fast FLIM imaging with 10 ps resolution, enabling high-speed analysis of dynamic processes in biological samples
Poster describing high-speed multichannel TCSPC electronics using SiGe time-to-digital converters, enabling 25 ps timing resolution and high-throughput photon timing.
Please fill out the form below to receive the requested file. After submitting your details, the file will be sent to you by email.
* Required
Please fill out the form below to request more information. You may also use it to inquire about pricing, availability, technical specifications, or discuss your specific application. Our sales team will be happy to review your request and get in touch with you. If additional information is needed to process your inquiry, we will let you know.
* Required
Explore alternative products within this category to compare specifications, performance, and configurations for your application.
Please fill out the form below to request more information about our products and services. You may also use it to ask for pricing, availability, technical specifications, or any other details relevant to your inquiry. Our team will be happy to review your request and get in touch with you. If additional information is needed to process your inquiry, we will let you know.
* Required
Please fill out the form below to request more information and prices about our product. Our team will be happy to review your request and get in touch with you. If additional information is needed to process your inquiry, we will let you know.
* Required