TimeHarp 260

TCSPC and MCS Board with PCIe Interface

Integrate precise time tagging and TCSPC into your system with a compact PCIe board for OEM, education, and entry-level applications.
TimeHarp 260 TCSPC and MCS PCIe board for photon counting measurements

Key Features

Compact form factor for system integration
Single and Dual channel configuration
“PICO” and “NANO” models for differing performance requirements

High-Performance Time Tagging & TCSPC PCIe Board

Time Tagging and TCSPC Board with PCIe Interface

TimeHarp 260 is a compact, PCIe-based time tagging and TCSPC card designed for straightforward system integration and reliable photon-counting performance. Based on a custom TDC architecture, it delivers precise picosecond timing with ultrashort dead time and supports high-throughput operation. Available in PICO and NANO versions as well as SINGLE and DUAL configurations, TimeHarp 260 offers flexible performance as well as detector and synchronization channel options.

TimeHarp 260 addresses OEM and seamless system-integration scenarios across all disciplines as well as entry-level and educational photon-counting applications. It provides a practical platform for learning, prototyping, and deploying time-resolved measurement techniques where reliable picosecond timing and tight system integration are required. Engineered for long-term reliability and seamless integration, TimeHarp 260 comes with a 5-year warranty.

Specifications

TimeHarp 260 PICOTimeHarp 260 NANO
Number of detector channels (in addition to sync)1 (SINGLE) or 2 (DUAL)1 (SINGLE) or 2 (DUAL)
Input voltage range (pulse peak into 50 Ohms)0 to - 1200 mV, optimum: - 100 mV to - 200 mV- 1200 mV to + 1200 mV
Input voltage max. range (damage level)± 1500 mV± 2500 mV
Trigger methodFalling edgeFalling or rising edge, software adjustable
TimeHarp 260 PICOTimeHarp 260 NANO
Minimum time bin width25 ps; in optional "long range mode": 2.5 ns250 ps*
Timing precision**< 20 ps RMS; in optional "long range mode": < 1 ns RMS< 250 ps RMS*
Timing precision / √2**< 14 ps RMS; in optional "long range mode": < 710 ps RMS< 180 ps RMS*
Dead time< 25 ns; in optional "long range mode": < 2.5 ns< 2 ns
Differential non-linearity< 2 % peak; < 0.2 % RMS (over full measurement range)< 2 % peak; < 0.2 % RMS (over full measurement range)
Maximum sync rate (periodic pulse train)100 MHz100 MHz
TimeHarp 260 PICOTimeHarp 260 NANO
Count depth32 bit (4 294 967 296 counts)32 bit (4 294 967 296 counts)
Maximum number of time bins32 76832 768
TimeHarp 260 PICOTimeHarp 260 NANO
Sustained throughput (sum of all channels)***40 Mcps40 Mcps
TimeHarp 260 PICOTimeHarp 260 NANO
PeriodProgrammable, 0.1 µs to 1678 s (0.596 Hz to 10 MHz)Programmable, 0.1 µs to 1678 s (0.596 Hz to 10 MHz)
TimeHarp 260 PICOTimeHarp 260 NANO
Number4 (only available in DUAL models with 2 detection channels)4 (only available in DUAL models with 2 detection channels)

* applies to TimeHarp 260 Nano with base resolution = 250 ps (shipped after 2015). Earlier boards have a resolution of 1 ns but can be returned for an upgrade to 250 ps upon request.

** In order to determine the timing precision it is necessary to repeatedly measure a time difference and to calculate the standard deviation (RMSerror) of these measurements. This is done by splitting an electrical signal from a pulse generator and feeding the two signals each to a separate input channel. The differences of the measured pulse arrival times are calculated along with the corresponding standard deviation. This latter value is the RMS jitter which we use to specify the timing precision. However, calculating such a time difference requires two time measurements. Therefore, following from error propagation laws, the single channel RMS error is obtained by dividing the previously calculated standard deviation by √2. We also specify this single channel RMS error here for comparison with other products.

*** Sustained throughput depends on configuration and performance of host PC

**** AMD processor chips recommended

 

All Information given here is reliable to our best knowledge. However, no responsibility is assumed for possible inaccuracies or omissions. Specifications and external appearances are subject to change without notice.

Technical Documentation and Data

Technical Downloads

Datasheet TimeHarp 260

Contains specifications, features and applications of the TCSPC and MCS PCIe board offering high timing resolution and time tagging

Technical Note: Phosphorescence Lifetime Imaging Microscopy Measurements

Coveres measurement principles, instrumentation, TCSPC detection, and applications in materials and life sciences

Technical Note: TCSPC

Explaining the principles of time-correlated single photon counting (TCSPC), including photon statistics, detectors, timing electronics, and applications.

Key Capabilities and Application Insights

Explore how advanced time tagging, correlation analysis, and high-speed TCSPC electronics enable precise photon-counting measurements across a wide range of scientific applications.

Diagram illustrating T2 and T3 time tagging architectures used in TCSPC systems to record photon arrival times.

TTTR: Full Photon-by-Photon Time Tagging

Time-Tagged Time-Resolved (TTTR) mode records every photon event with its exact arrival time and channel assignment, enabling detailed offline analysis of fluorescence dynamics, correlation processes, and single-molecule behavior. It supports applications ranging from FCS and burst analysis to fast FLIM and quantum optics. Both T2 and T3 modes are available, covering free-running timing across all inputs. Dual-channel versions can also capture external marker events for precise synchronization with scanners and other hardware. Learn more about TTTR in our blog article.

FLIM image of RuBiPy crystals showing luminescence lifetime distribution

Technology Insight: High-Speed TCSPC Electronics Based on SiGe TDCs

TimeHarp 260 is built on a custom time-to-digital converter (TDC) architecture developed using fast SiGe technology, enabling picosecond timing, ultrashort dead time, and high sustained count rates. The poster “High Speed Multichannel TCSPC Electronics” provides an in-depth look at the underlying hardware design, including the multichannel TDC layout, FPGA-based data processing pipeline, and the memory-efficient event handling used for time tagging and correlation measurements. It also highlights the Long Range Mode, which extends the measurable time window for phosphorescence and long-lived decay processes into the second range while maintaining excellent timing performance. Test data, correlation measurements, and FLIM examples illustrate the robustness and precision of the electronics across a wide range of photon-counting applications.

Coincidence correlation showing photon antibunching of NV centers in nanodiamonds

Coincidence Correlation and Photon Antibunching

Coincidence correlation measurements on a picosecond timing scale are a powerful tool in life sciences and quantum optics. In quantum optics, they are used to investigate phenomena such as photon antibunching, quantum entanglement, and single-photon emission. By correlating photon arrival times from multiple detectors, it becomes possible to determine whether an emitter behaves as a true single-photon source. The example shown demonstrates antibunching from nitrogen vacancy (NV) centers in nanodiamonds, confirming the presence of a single quantum emitter.

Software for Intuitive Operation and Custom Workflows

TimeHarp 260 is supported by intuitive acquisition software for fast setup, live monitoring, and clear data visualization, while flexible programming interfaces enable custom automation and experiment control. From ready-to-use GUI operation with UniHarp to scripting and integration via Python, C/C++, LabVIEW, and MATLAB using snAPI and programming libraries, the platform adapts seamlessly to both routine measurements and advanced, application-specific workflows.

UniHarp software interface displaying time resolved histogram measurement data

UniHarp: Intuitive TCSPC Data Acquisition

UniHarp is PicoQuant’s free data acquisition software for TCSPC and time-tagging devices, offering real-time control, clean visualization, and flexible data saving. It supports time traces, histograms, correlation measurements (including g² and FCS), and provides an easy, intuitive workflow for configuring and running experiments.

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snAPI Python interface for controlling PicoQuant Time Tagging & TCSPC electronics.

snAPI: Fast Python Access for Custom Workflows

snAPI is PicoQuant’s efficient Python interface for TCSPC hardware, enabling streamlined device communication, configuration, and data handling. It allows users to build custom scripts, automation routines, and analysis pipelines with minimal overhead.

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Relevant for Your Research​

Matching Applications & Methods​

Switcher A&M
Concept illustration of optical environmental sensing where time-resolved fluorescence lifetime detection monitors dynamic environmental signals and trace compounds.
Life Science | Materials Science | Metrology
Schematic illustration of nanostructured materials on a substrate highlighting heterogeneous nanoscale architectures studied by optical and time-resolved characterization.
Materials Science
In-Depth Scientific Resources

Scientific Resources

Access in-depth application notes and scientific posters with detailed methods, measurement data, and real-world use cases.

Application Note: High-Speed Protein Lifetime Measurements

This application note demonstrates high-speed protein lifetime measurements using a 280 nm picosecond laser for sensitive time-resolved fluorescence spectroscopy.

Application Note: Visualize Dynamic Processes with rapidFLIM HiRes

Application note on rapidFLIM HiRes for fast FLIM imaging with 10 ps resolution, enabling high-speed analysis of dynamic processes in biological samples

Poster: High Speed Multichannel TCSPC Electronics

Poster describing high-speed multichannel TCSPC electronics using SiGe time-to-digital converters, enabling 25 ps timing resolution and high-throughput photon timing.

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