
Complete confocal fluorescence microscope that empowers researchers to advance quantitative functional imaging from individual molecules to cells and tissues.

Modular, customizable, time-resolved confocal microscope with single-molecule sensitivity for life and materials science.

Compact FLIM and FCS upgrade kit that adds advanced functional imaging and correlation analysis to existing laser scanning microscopes.

Designed for flexible, sensitive, and precise steady-state and time-resolved spectroscopy across the UV to NIR range and time scales from picoseconds to milliseconds.

Modular lifetime spectrometer designed for flexible fluorescence and photoluminescence measurements in both materials and life science research.

Add spectral and time-resolved photoluminescence to your setup through flexible microscope–spectrometer coupling options.

Get the most out of superconducting nanowire detectors in large-scale quantum communication and computing experiments requiring precise multichannel timing.

Boost your time-resolved experiments with a flexible, high-precision time tagging and TCSPC unit for materials science and quantum sensing.

Scale your photonic quantum computing and detector characterization setups while maintaining performance, flexibility, and high data throughput.

Compact 3-color picosecond laser delivering flexible ns to ms excitation with cost-effective multicolor performance and straightforward operation.

Smart picosecond laser diode heads covering UV-A to NIR, providing the right combination of power, pulse width, and diode type for any time-resolved technique.

VisUV provides clean short pulses and stable timing across key UV and visible wavelengths, including deep UV lines as well as 488 nm and 532 nm.

Enhance your single-photon counting experiments with wide dynamic range and excellent timing precision in the UV and visible even at the highest count rates.

Capture even the weakest signals over large areas with maximum dynamic range and enhanced low-light sensitivity in a compact detector design.

Unlock spatially resolved single-photon detection with a 23-pixel SPAD array, combining low dark counts and precise time tagging for advanced experiments.

Advanced FLIM analysis software for fast, accurate interpretation of lifetime imaging data.

Intuitive, free software solution for real-time, high-precision photon data acquisition, visualization, and initial data analysis.

Advanced software for time-resolved fluorescence acquisition and analysis.

An imaging technique that uses fluorescence lifetimes to generate image contrast.

Investigating how proteins dynamically explore multiple conformational states that control biological function.

Investigating how biomolecules separate into dynamic liquid phases to organize cellular space and regulate biological function.

A time-resolved technique that measures photoluminescence lifetimes to reveal excited-state dynamics in materials.

Studying exciton dynamics, charge carrier processes, and structural properties through optical and time-resolved characterization methods.

Investigating charge-carrier lifetimes and recombination dynamics to enable precise optical characterization of material quality and device performance.

A quantum optical signature revealed by time-resolved photon correlation analysis to identify single-photon emission in materials and nanostructures.

The transmission of information using individual photons, using quantum effects to ensure absolute security.

Quantifying photons per detection event enables direct access to photon-number statistics, providing insight into quantum and statistical properties of light.

An optical technique that analyzes light emission under electrical excitation to reveal electronic properties of electroluminescent materials.

Monitoring environmental signals and trace compounds to understand dynamic changes in natural and engineered environments.

A photon timing technique that measures single-photon arrival times to resolve ultrafast dynamics in fluorescence, materials research, and quantum optics.
PicoHarp 330 is PicoQuant’s signature timing electronics and the world’s first device that combines best timing resolution with flexible trigger options. At heart it offers a base resoltion of 1 ps, a timing jitter of 2 ps and an ultrashort dead time of below 680 ps together with selectable and configurable level triggers and constant fraction discriminators (CFD). Following an upgradable design with up to 5 input channels, the device is equipped with powerful on-board event filters, options for external synchronization and supports external markers.
PicoHarp 330 is ideally adapted for demanding experiments in material science and quantum sensing stretching, inter alia, time-resolved photoluminescence (TRPL) studies, quantum emitter characterization and optically-detected magnetic resonance (ODMR) techniques.
| Number of detector channels (in addition to Sync input) | 1 (Base model); 2, 3 or 4 (Base model + channel upgrades) |
| Input voltage operating range (pulse peak into 50 Ohms) | - 1500 mV to 1500 mV |
| Input voltage max. range (damage level) | U ≤ - 2000 mV; U ≥ 3000 mV |
| Trigger method | Level Trigger: falling or rising edge, software adjustable; CFD: falling edge |
| Minimum time bin width | 1 ps |
| Timing precision* | 3 ps RMS typ. |
| Timing precision / √2* | 2 ps RMS typ. |
| Dead time | 680 ps for edge trigger, 4.2 ns with CFD |
| Differential non-linearity | < 6 % peak, < 0.9 % RMS (over full measurement range) |
| Maximum sync rate (periodic pulse train) | 640 MHz |
| Count depth | 32 bit (4 294 967 295 counts) |
| Maximum number of time bins | 65 536 (via GUI), 524 288 (via DLL) |
| Peak count rate per input channel | 1.47 Gcps for 1000 events |
| Sustained count rate per input channels** | 80 Mcps |
| Total sustained count rate, sum over all input channels** | 85 Mcps via USB 3.0 interface |
| Period | Programmable, 0.1 μs - 1.678 s (0.596 Hz - 10 MHz) |
| Number | 4 |
| Ref. IN | 10 MHz, 100 MHz, or 500 MHz, 200 … 1500 mV p.p., 50 Ohm; AC coupled |
| Ref. OUT | Default: 10 MHz, 1000 mV, 50 Ohm; DC coupled |
*In order to determine the timing precision it is necessary to repeatedly measure a time difference and to calculate the standard deviation (RMS error) of these measurements. This is done by splitting an electrical signal from a pulse generator and feeding the two signals each to a separate input channel. The differences of the measured pulse arrival times are calculated along with the corresponding standard deviation. This latter value is the RMS jitter which we use to specify the timing precision. However, calculating such a time difference requires two time measurements. Therefore, following from error propagation laws, the single channel RMS error is obtained by dividing the previously calculated standard deviation by √(2). We also specify this single channel RMS error here for comparison with other products
** Sustained throughput depends on configuration and performance of host PC.
Provides detailed specifications of this precise TCSPC and time-tagging unit, offering picosecond timing, multichannel options, and fast data acquisition
PicoHarp 330 is supported by a comprehensive software environment that enables both immediate operation and advanced integration. An included Windows-based control software provides full access to measurement settings, real-time visualization and data management, while libraries for custom programming support integration into user-defined workflows and automated setups. Depending on the application and workflow, PicoHarp 330 can be operated using different software tools that cover data acquisition, custom programming, and advanced analysis.

UniHarp provides real time visualization, flexible data handling, intuitive parameter control and continuous monitoring of key metrics such as count rates, peak position and timing stability. Its streamlined interface supports a wide range of workflows from measurement classes such as histogramming and correlation to Manipulators such as Coincidence and Herald and offers a robust starting point for time-resolved experiments.

snAPI is PicoQuant’s high level Python interface for custom programming and automated workflows. It provides efficient device control, access to the raw time tag stream and ready to use demo scripts for histogramming, time traces, coincidence extraction, g2 correlation and FCS. snAPI enables fast integration into complex experimental and data processing environments.

The PicoHarp 330 integrates with PicoQuant’s advanced software suites including SymPhoTime 64 for time resolved imaging and QuCoa for quantum optics correlation analysis. These tools offer extended capabilities for specialized workflows and complement the core functionality of UniHarp and snAPI.
PicoHarp 330 combines advanced time-tagging capabilities with flexible trigger configurations to support a wide range of time-resolved photon experiments.

PicoQuant‘s revolutionary TTTR mode records every detected photon as an individual time-tag event without early data reduction, preserving the full timing information of the experiment. This enables advanced analyses such as photon burst detection, detailed fluorescence dynamics, FCS, g2 correlation and high speed FLIM with unlimited image size. TTTR is also widely used in single molecule spectroscopy, time interval analysis and quantum optics. A dedicated blog article will provide a deeper introduction to TTTR, its modes and its application range.

In order to support the widest possible variety of single photon detectors, the PicoHarp 330 provides different input circuitry. For optimal timing with e.g. Single-Photon Avanlanche Diodes (SPADs) the inputs can be configured as level triggers while for best performance with Hybrid Photodetectors (HPD), Photomultiplier Tubes (PMTs), Micro Channel Plates (MCPs) or Superconducting Nanowire Single-Photon Detectors (SNSPDs) at high count rates they can be configured as Constant Fraction Discriminators (CFD). This way the overall system IRF may be tuned to become narrower. The same could not be achieved with a simple level trigger (comparator). Particularly with PMTs and MCPs, constant fraction discrimination is very important as their pulse amplitudes vary significantly.
Application note on rapidFLIM HiRes for fast FLIM imaging with 10 ps resolution, enabling high-speed analysis of dynamic processes in biological samples
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