PicoQuant has released a new design of the FluoTime 300 fluorescence lifetime spectrometer. The sample chamber of the system is now designed around modular sample holders, which allow a quick and easy change between different sample configurations, e. g. liquids, powders, or wafers. The range of available sample holders was also extended and now includes a front face sample holder for samples of up to 2 inch size. The holder permits to change position and angle of the sample with respect to the direction of excitation and detection from outside of the sample compartment. This special feature is extremely useful for an on-line optimization of the beam position on the sample while the measurement is running.