September 5, 2016

rapidFLIM – redefining the standards for dynamic FLIM imaging

PicoQuant releases application note describing a novel fluorescence lifetime imaging method with fast image acquisition

A recent publication by PicoQuant lays out the basics of rapidFLIM, a novel, dynamic Fluorescence Lifetime Imaging (FLIM) method, along with practical applications. The rapidFLIM approach allows image acquisition with several frames per second and thus opens the way for the study of dynamic processes in living cells or other materials through fast fluorescence lifetime imaging. It is ideally suited for observing fast processes, like protein interaction or chemical interactions, following highly mobile species including live cells, moving organelles, or nanoparticles, as well as investigate Förster Resonance Energy Transfer (FRET) dynamics. Depending on sample brightness and image size, rapidFLIM allows acquiring more than 10 to 15 frames per second.

July 5, 2016

PicoQuant expands its VisUV picosecond pulsed laser platform

PicoQuant has introduced two new pulsed laser modules VisUV-1064 and VisUV-532-HP, rounding out the VisUV platform line-up. Up to now, modules based on this platform provided laser pulses at 266 nm, 355 nm, and 532 nm, either individually or in combination with one or two other wavelengths. The new VisUV-1064 emits picosecond pulsed laser light at 1064 nm with an average optical power of more than 1 W, while the VisUV-532-HP provides high-powered sub nanosecond pulses at 532 nm with an average optical power of up to 750 mW.

April 12, 2016

PicoQuant’s LSM upgrade kit now supports the Olympus FluoView FV3000

New upgrade kit expands the capabilities of the laser scanning microscope Olympus FluoView FV3000 with time-resolved analysis

PicoQuant GmbH has expanded the compatibility list of its FLIM and FCS upgrade kit to include the Olympus FV3000 confocal laser scanning microscope (CLSM). The upgrade kit is an external addition to the CLSM enhancing its capabilities by the addition of time-resolved techniques such as fluorescence lifetime imaging (FLIM), Fluorescence Correlation Spectroscopy (FCS), or advanced time-resolved Förster Resonance Energy Transfer (FRET) analysis. Even the new approach rapidFLIM for very fast and accurate FLIM imaging is available.

February 10, 2016

Integration of Bruker’s BioScope Resolve BioAFM into the MicroTime 200

Time-resolved microscope is ready for the full integration of Bruker's BioScope Resolve BioAFM

PicoQuant announces that its modular, time-resolved fluorescence microscope MicroTime 200 is ready for integration of the atomic force microscope (AFM) BioScope Resolve BioAFM from Bruker, joining the line-up of compatible AFMs.

January 5, 2016

TimeHarp 260 Nano with improved time resolution is now available

An improved model of the TCSPC and MCS board TimeHarp 260 Nano with a time resolution of 250 ps has been released

An improved model of the TimeHarp 260 Nano has been release along with an updated version of the TimeHarp software. The improved PCIe board features now a time resolution of 250 ps.