News and Press Releases

December 18, 2025

New Technical Note. Metabolic State Profiling of Organoids with FLIM

Our new Technical Note demonstrates the possibility of identifying distinct metabolic profiles of organoids using Fluorescence Lifetime Imaging (FLIM) of autofluorescence arising from different bound and unbound states of NAD(H) under two-photon excitation.

Fluorescence lifetime images were acquired using the Luminosa single-photon counting laser scanning confocal microscope from PicoQuant. Luminosa combines intuitive workflows, online image previews for real-time quality assessment, and advanced, fast GPU-based analysis routines. The fully motorized microscope system enables quick auto-alignment and power calibration for streamlined FLIM operation.

The images were further analyzed using NovaFLIM software, which allows seamless application of various analysis methods, including phasor plots, FastLifetime contrast, multi-exponential fitting, and pattern-matching analysis.

Read the full Technical Note here.

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November 14, 2025

Workshop Announcement: Photoluminescence Spectroscopy in Materials Research — February 19–20, 2026

PicoQuant is pleased to support an upcoming 1.5-day workshop on photoluminescence spectroscopy in materials research, taking place February 19–20, 2026 at TU Wien in Vienna, Austria. The event is organized by MECS and hosted by the Eder Group at TU Wien in collaboration with PicoQuant.

Participants will have the opportunity to explore the latest advances in photoluminescence methods, attend expert presentations, and take part in hands-on sessions featuring PicoQuant’s FluoTime 300 photoluminescence spectrometer and FluoMic microscope. Invited speakers include Ute Resch-Genger (BAM Berlin) and Filip Mravec (Brno University of Technology).

Registration is free of charge and open until January 15, 2026.

Register now to secure your spot >

September 29, 2025

PicoQuant celebrates 30th Single Molecule Workshop in Berlin

More than 250 researchers from across the globe came together to share insights and explore emerging trends

“The 30th workshop was an inspiring platform – shaped by exceptional expertise, lively exchange, and young talent. We thank all participants. Together we are writing the next chapters in single molecule research.”

Rainer Erdmann, CEO of PicoQuant

PicoQuant successfully concluded the 30th International Workshop on Single Molecule Spectroscopy and Super-Resolution Microscopy in Berlin. From September 23–26, 2025, a record number of 250 participants joined to celebrate three decades of global scientific exchange.

The anniversary edition featured an outstanding program with Nobel Laureates Stefan W. Hell (Max Planck Institute for Multidisciplinary Sciences) and W.E. Moerner (Stanford University) among the speakers. Leading researchers shared the latest advances in FLIM, smFRET, FCS/FLCS, Single Molecule Localization Microscopy, as well as new approaches in machine learning and open-source analysis.

September 23, 2025

PicoQuant Invests in FluoBrick Solutions to Simplify Access to Single Molecule Research

Partnering to make advanced fluorescence techniques intuitive, affordable, and accessible

“I am really thrilled to build on the outcomes of my PhD project, to enable scientists to gain faster and deeper insights into complex protein interactions and single-particle detection without the need for significant investment or prior expertise in advanced fluorescence methods.” – Dr. Gabriel Moya, founder of FluoBrick Solutions

PicoQuant GmbH has invested in FluoBrick Solutions GmbH, a Berlin-based start-up dedicated to lowering the barriers to single-molecule techniques such as Fluorescence Correlation Spectroscopy (FCS) and Förster Resonance Energy Transfer (FRET). The 2025 spin-off from LMU Munich develops ready-to-use instruments that help researchers study proteins and oligonucleotides at the single-molecule level, saving time and sample material while accelerating workflows.

August 27, 2025

High-Precision Photon Counting for Quantum Research

Intuitive setup, live FWHM analysis, and in-measurement adjustments

Accurate timing is essential when investigating quantum dots, NV centers, or entangled photon sources. A powerful combination of software and hardware enables precise g²(τ), lifetime, and coincidence measurements across a wide range of quantum optics experiments.

A powerful integration of software and hardware:

UniHarp DAQ Software
Offers an intuitive interface for photon correlation experiments, with real-time FWHM analysis and parameter adjustments during acquisition. Ideal for streamlining setup and analysis in g²(τ) and TCSPC applications.

Precise and Versatile Time Tagging and TCSPC Unit PicoHarp 330
A compact time tagger with 1 ps resolution, 680 ps dead time, and TTTR mode. Well-suited for HBT configurations and photon statistics analysis where space and channel count are limited.

High-Resolution Multichannel Time Tagging and TCSPC Unit HydraHarp 500
Designed for demanding quantum experiments, it features up to 16 input channels, low dead time, and synchronization options such as White Rabbit. A flexible solution for multi-channel correlation and time-tagging setups.