News and Press Releases

January 23, 2026

New Features Luminosa 2.0 New workflow for FRAP and a Python interface.

This powerful new addition brings even more flexibility and performance.

Luminosa got many new features, including a new workflow for FRAP and a Python interface.

Software is ready for Download.

LumiPy: A Python interface enabling adaptive workflows, custom acquisition, and reporting, but also allowing researchers to bring open-source, Python-based projects as close as possible to the microscope.

Fluorescence Recovery After Photobleaching (FRAP): A context-based workflow for FRAP complementing the Luminosa toolbox for the study of biocondensates.

New functions for LumiFinder:
    • Automatically use different excitation power for emitter identification and time-trace measurements to avoid unnecessary photobleaching.
    • More stopping criteria for the time-trace measurement offer more flexibility in single-molecule FRET measurements of immobilized molecules.

January 16, 2026

Time Tagger for Highest-Throughput Applications Ahead

New Standards for Data Throughput and Scalability

We are preparing to expand the HydraHarp family with the upcoming HydraHarp 500 L. This new variant will set new standards for data throughput and scalability. With outstanding timing resolution, excellent timing precision and up to 64 flexible channels, the HydraHarp 500 L is engineered for highest-throughput applications powered – for the first time – by USB 3.2 Gen 2×2, making it ideal for rapid, large-volume data acquisition.

December 18, 2025

New Technical Note. Metabolic State Profiling of Organoids with FLIM

Our new Technical Note demonstrates the possibility of identifying distinct metabolic profiles of organoids using Fluorescence Lifetime Imaging (FLIM) of autofluorescence arising from different bound and unbound states of NAD(H) under two-photon excitation.

Fluorescence lifetime images were acquired using the Luminosa single-photon counting laser scanning confocal microscope from PicoQuant. Luminosa combines intuitive workflows, online image previews for real-time quality assessment, and advanced, fast GPU-based analysis routines. The fully motorized microscope system enables quick auto-alignment and power calibration for streamlined FLIM operation.

The images were further analyzed using NovaFLIM software, which allows seamless application of various analysis methods, including phasor plots, FastLifetime contrast, multi-exponential fitting, and pattern-matching analysis.

Read the full Technical Note here.

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November 14, 2025

Workshop Announcement: Photoluminescence Spectroscopy in Materials Research — February 19–20, 2026

PicoQuant is pleased to support an upcoming 1.5-day workshop on photoluminescence spectroscopy in materials research, taking place February 19–20, 2026 at TU Wien in Vienna, Austria. The event is organized by MECS and hosted by the Eder Group at TU Wien in collaboration with PicoQuant.

Participants will have the opportunity to explore the latest advances in photoluminescence methods, attend expert presentations, and take part in hands-on sessions featuring PicoQuant’s FluoTime 300 photoluminescence spectrometer and FluoMic microscope. Invited speakers include Ute Resch-Genger (BAM Berlin) and Filip Mravec (Brno University of Technology).

Registration is free of charge and open until January 15, 2026.

Register now to secure your spot >

September 29, 2025

PicoQuant celebrates 30th Single Molecule Workshop in Berlin

More than 250 researchers from across the globe came together to share insights and explore emerging trends

“The 30th workshop was an inspiring platform – shaped by exceptional expertise, lively exchange, and young talent. We thank all participants. Together we are writing the next chapters in single molecule research.”

Rainer Erdmann, CEO of PicoQuant

PicoQuant successfully concluded the 30th International Workshop on Single Molecule Spectroscopy and Super-Resolution Microscopy in Berlin. From September 23–26, 2025, a record number of 250 participants joined to celebrate three decades of global scientific exchange.

The anniversary edition featured an outstanding program with Nobel Laureates Stefan W. Hell (Max Planck Institute for Multidisciplinary Sciences) and W.E. Moerner (Stanford University) among the speakers. Leading researchers shared the latest advances in FLIM, smFRET, FCS/FLCS, Single Molecule Localization Microscopy, as well as new approaches in machine learning and open-source analysis.