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January 23, 2026

New Features Luminosa 2.0 New workflow for FRAP and a Python interface.

This powerful new addition brings even more flexibility and performance.

Luminosa got many new features, including a new workflow for FRAP and a Python interface.

Software is ready for Download.

LumiPy: A Python interface enabling adaptive workflows, custom acquisition, and reporting, but also allowing researchers to bring open-source, Python-based projects as close as possible to the microscope.

Fluorescence Recovery After Photobleaching (FRAP): A context-based workflow for FRAP complementing the Luminosa toolbox for the study of biocondensates.

New functions for LumiFinder:
    • Automatically use different excitation power for emitter identification and time-trace measurements to avoid unnecessary photobleaching.
    • More stopping criteria for the time-trace measurement offer more flexibility in single-molecule FRET measurements of immobilized molecules.

Press Release
New Features Luminosa 2.0  New workflow for FRAP and a Python interface.

January 16, 2026

Time Tagger for Highest-Throughput Applications Ahead

New Standards for Data Throughput and Scalability

We are preparing to expand the HydraHarp family with the upcoming HydraHarp 500 L. This new variant will set new standards for data throughput and scalability. With outstanding timing resolution, excellent timing precision and up to 64 flexible channels, the HydraHarp 500 L is engineered for highest-throughput applications powered – for the first time – by USB 3.2 Gen 2×2, making it ideal for rapid, large-volume data acquisition.

Press Release
Time Tagger for Highest-Throughput Applications Ahead

December 18, 2025

New Technical Note. Metabolic State Profiling of Organoids with FLIM

Our new Technical Note demonstrates the possibility of identifying distinct metabolic profiles of organoids using Fluorescence Lifetime Imaging (FLIM) of autofluorescence arising from different bound and unbound states of NAD(H) under two-photon excitation.

Fluorescence lifetime images were acquired using the Luminosa single-photon counting laser scanning confocal microscope from PicoQuant. Luminosa combines intuitive workflows, online image previews for real-time quality assessment, and advanced, fast GPU-based analysis routines. The fully motorized microscope system enables quick auto-alignment and power calibration for streamlined FLIM operation.

The images were further analyzed using NovaFLIM software, which allows seamless application of various analysis methods, including phasor plots, FastLifetime contrast, multi-exponential fitting, and pattern-matching analysis.

Read the full Technical Note here.

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New Technical Note. Metabolic State Profiling of Organoids with FLIM

November 14, 2025

Workshop Announcement: Photoluminescence Spectroscopy in Materials Research — February 19–20, 2026

PicoQuant is pleased to support an upcoming 1.5-day workshop on photoluminescence spectroscopy in materials research, taking place February 19–20, 2026 at TU Wien in Vienna, Austria. The event is organized by MECS and hosted by the Eder Group at TU Wien in collaboration with PicoQuant.

Participants will have the opportunity to explore the latest advances in photoluminescence methods, attend expert presentations, and take part in hands-on sessions featuring PicoQuant’s FluoTime 300 photoluminescence spectrometer and FluoMic microscope. Invited speakers include Ute Resch-Genger (BAM Berlin) and Filip Mravec (Brno University of Technology).

Registration is free of charge and open until January 15, 2026.

Register now to secure your spot >

Workshop Announcement: Photoluminescence Spectroscopy in Materials Research — February 19–20, 2026

August 27, 2025

High-Precision Photon Counting for Quantum Research

Intuitive setup, live FWHM analysis, and in-measurement adjustments

Accurate timing is essential when investigating quantum dots, NV centers, or entangled photon sources. A powerful combination of software and hardware enables precise g²(τ), lifetime, and coincidence measurements across a wide range of quantum optics experiments.

A powerful integration of software and hardware:

UniHarp DAQ Software
Offers an intuitive interface for photon correlation experiments, with real-time FWHM analysis and parameter adjustments during acquisition. Ideal for streamlining setup and analysis in g²(τ) and TCSPC applications.

Precise and Versatile Time Tagging and TCSPC Unit PicoHarp 330
A compact time tagger with 1 ps resolution, 680 ps dead time, and TTTR mode. Well-suited for HBT configurations and photon statistics analysis where space and channel count are limited.

High-Resolution Multichannel Time Tagging and TCSPC Unit HydraHarp 500
Designed for demanding quantum experiments, it features up to 16 input channels, low dead time, and synchronization options such as White Rabbit. A flexible solution for multi-channel correlation and time-tagging setups.

High-Precision Photon Counting for Quantum Research