May 7, 2020

Leveraging undesired cross-labeling effects in indirect immunofluorescence

A recent article in Scientific Reports presents a novel FLIM based approach

In an excellent work of former Marie Curie Research Fellow at PicoQuant Sumeet Rohilla and the group of Andreas Hocke from the Charité Universitätsmedizin, a novel FLIM based approach has been introduced in an article in Scientific Reports for leveraging undesired cross-labeling effects in indirect immunofluorescence (IMF). The increased specificity allowed for the seperation of various standard antibody-based labels with increased specificity using spectral FLIM and pattern matching. Consequently, no establishment of new anti-body labeling protocols is required for avoiding cross-labeling which saves cost and time while misinterpretation such as wrongly attributed spatial distribution of biomolecules is avoided.

The paper is available at nature.com: https://www.nature.com/articles/s41598-020-60877-8

April 16, 2020

New white paper on measuring steady-state and time-resolved photoluminescence

Free pdf for download

Read our recent white paper where we demonstrate how the new FluoMic add-on for the FluoTime 300 time-resolved fluorescence spectrometer becomes a powerful tool for collecting spectral and temporal information using a micrometer-sized positionable observation volume. This combination is an excellent way to learn more about your samples, especially in materials science!

Title of the White Paper: Measuring steady-state and time-resolved photoluminescence from a positionable, micrometer-sized observation volume with the FluoMic add-on.

Download pdf of the white paper.

April 9, 2020

PicoQuant releases microbiologist from his work to help in the fight against COVID-19

Being a reserve officer Dr. Fabian Jolmes has been asked by the Bundeswehr for temporal support in the Bundeswehr Hospital

Dr. Fabian Jolmes, microbiologist and application specialist for confocal microscopy at PicoQuant will be on a temporal leave for several months to help in the fight against the COVID-19 pandemic. Being a reserve officer of the Federal Defence Forces of Germany (Bundeswehr) he has been asked for his support in the execution and evaluation of COVID-19 tests. Supporting such an important social task is a matter of course for us at PicoQuant. Managing Director Rainer Erdmann did not hesitate a second to approve Fabians release from his regular work when the request from the Bundeswehr arrived. Fabian started his work in the department of microbiology of the Bundeswehr Hospital in Berlin this week - Stay healthy Fabian!

April 9, 2020

PicoQuant combines high timing precision with ultrashort dead time

New versions of the high-throughput multichannel event timer MultiHarp 150 with 10 ps digital resolution are now available

PicoQuant releases three new models of the high-throughput multichannel event timer MultiHarp 150: MultiHarp 150 4P, 8P, and 16P. The units with either 4, 8, or 16 detection channels offer improved timing precision with 10 ps minimum bin width, along with jitter better than 45 ps (root mean square). This is the best time resolution for event timers with sub-nanosecond dead time available on the market. The new MultiHarp 150 models are PicoQuant's latest benchmark TCSPC electronics for fast and high-resolution fluorescence lifetime imaging (rapidFLIM) and multichannel photon correlation.

March 30, 2020

Our support team offers remote demos

Demos of our spectroscopy and microscopy systems and their respective software

As we may not travel to our customers nor receive visitors right now due to the COVID-19 pandemic, our support team offers individual remote demos of our spectroscopy and microscopy systems and their respective software. A demo session can include a short introduction to the hardware as well as an introduction to methodologies such as FLIM, FCS, Pattern Matching. Sessions tailored to the needs of current users of our hardware are also available.

Simply contact our support team to make an appointment: http://www.picoquant.com/remote_demos