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June 25, 2020

User‐friendly single‐photon source operating at telecom wavelengths

PicoQuant developed the dedicated picosecond pulsed diode laser

A user‐friendly, fiber‐coupled, single‐photon source operating at telecom wavelengths is presented on the latest cover of "Advanced Quantum Technologies". This single-photon source is the result of a joint German-Polish project ("FI-SEQUR") with partners Wrocław University of Science and Technology, Technische Universität Berlin, Maria Curie Sklodowska University Lublin, Fibrain Sp. z o.o, JCMwave GmbH and PicoQuant. In this project, PicoQuant has developed a dedicated picosecond pulsed diode laser to efficiently excite a quantum dot that launches single photons at a wavelength of 1.3 µm directly into a single‐mode optical fiber. The whole arrangement is integrated into a 19ʺ compatible housing to enable stand‐alone operation by cooling via a compact Stirling cryocooler. The realized source delivers single photons with a multiphoton events probability as low as 0.15 and a single‐photon emission rate of up to 73 kHz into a standard telecom single‐mode fiber.

Paper: https://onlinelibrary.wiley.com/doi/10.1002/qute.202000018
PicoQuant's pulsed diode lasers: https://www.picoquant.com/products/category/pulsed-lasers-and-leds
 

User‐friendly single‐photon source operating at telecom wavelengths

June 22, 2020

Call for papers BiOS 2021

Conference on Single Molecule Spectroscopy and Superresolution Imaging

Within the framework of the Biomedical Optics Symposium BiOS, PicoQuant is co-organizing the special conference "Single Molecule Spectroscopy and Superresolution Imaging XIV" (BO503) during SPIE Photonics West in January 2021. Abstract due date is July 15, 2020.

As a special motivation for young researchers, PicoQuant is presenting the "Young Investigator Award" as part of this meeting. Young scientists (age 32 or below and not yet full faculty members) are encouraged to participate in this best paper competition which offers a cash award worth 1000 USD.

Abstract submission website: https://spie.org/PWB/conferencedetails/single-molecule-spectroscopy

Call for papers BiOS 2021

June 19, 2020

Study on membrane asymmetry

Measured with a Nikon A1 confocal equipped with PicoQuant´s LSM upgrade kit

Recently Ilya Levental, Assistant Professor of Integrative Biology and Pharmacology at The University of Texas Health Science Center at Houston toghether with his coworkers published an impressive study in Nature Chemical Biology in which FLIM and FCS, combined with a smart staining protocol and atomistic simulations, shed light on the structural asymmetry of plasma membranes. FLIM of the lipid packing reporter dye Di4, which enables leaflet-selective staining of the plasma membrane, revealed that the outer leaflet is more tightly packed. Correspondingly, FCS diffusion measurements of fluorescent proteins anchored either to the outer or inner leaflet were consistent with computational predictions that inner leaflet components diffuse faster. For this work, they used their Nikon A1 confocal equipped with PicoQuant´s LSM upgrade kit.

Paper: www.nature.com/articles/s41589-020-0529-6
PicoQuant's LSM upgrade kit: product website

Study on membrane asymmetry

May 20, 2020

Jörg Enderlein and Christian Eggeling about scanning FCS

Significance and advantages of this method

A new line scan mode in our SymPhoTime 64 software now allows acquiring scanning Fluorescence Correlation Spectroscopy (sFCS) data with our time-resolved microscope MicroTime 200. In interviews that were given during our 25th Workshop on “Single Molecule Spectroscopy and Super-resolution Microscopy” in September 2019 by Jörg Enderlein from the Georg-August-University Göttingen, Germany and Christian Eggeling from the Friedrich-Schiller-University Jena, Germany, they also talked about the significance and advantages of scanning FCS.

Video: Jörg Enderlein and Christian Eggeling about scanning FCS

Product website: MicroTime 200

Application website: Scanning FCS

Jörg Enderlein and Christian Eggeling about scanning FCS

May 19, 2020

Visit our application lab virtually and perform real measurements

Remote demos of our spectroscopy and microscopy systems and their respective software

Even as the world is slowly moving towards a “new normal”, we are not yet able to visit or welcome every customer in person. However, we want to invite you for a virtual stay in our application lab. There you can get a closer look at our spectroscopy and microscopy systems and have in-depth discussions with our application specialists from the safety and comfort of your own place. These remote demo sessions are not limited to just talking about instrument specifications or theoretical aspects. We are also more than happy to perform real measurements together with you using samples that you send us.

Make an appointment

Visit our application lab virtually and perform real measurements

Important Dates

Free webinar: rapidFLIM HiRes

The webinar will be held on Oct. 1, 2020.


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