| TCSPC and MCS Modules |
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Multichannel Picosecond Event Timer & TCSPC Module  |
HydraHarp 400 |
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The HydraHarp 400 picosecond event timer & TCSPC module is a modular system for picosecond time-resolved measurements. The system features a time resolution down to 1 picosecond, up to 8 independent but synchronized input channels with multi-stop capability and a Time-Tagged Time-Resolved (TTTR) mode with an unlimited measurement range at full resolution. A common sync input for all channels permits to use the system for TCSPC in forward start-stop mode at stable excitation sources up to 150 MHz. The HydraHarp 400 is connected to the PC via a USB 2.0 or USB 3.0 interface. A library (DLL) supports custom programming in e.g. C/C++, Delphi, Visual Basic and LabVIEW.
 The HydraHarp 400 is now available with a USB 3.0 interface, which improves data throughput as much as 5-fold. The histogrammer range has also been extended and now covers time spans from 65 ns to 2.19 s.
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Stand Alone TCSPC Module with USB Interface |
PicoHarp 300 |
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The PicoHarp 300 stand alone TCSPC module is a complete system for picosecond time-resolved measurements. It is connected to the PC via a USB 2.0 high speed interface. The system features a time resolution down to 4 picoseconds, two independent input channels with multi-stop capability and a Time-Tagged Time-Resolved (TTTR) mode with an unlimited measurement range at full resolution. In combination with an MCP-PMT or a fast SPADs, an overall instrument response function down to 50 ps can be achieved. A library (DLL) supports custom programming in e.g. C/C++, Delphi, Visual Basic and LabVIEW. |
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TCSPC and MCS board with PCIe interface |
TimeHarp 260 |
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The TimeHarp 260 is a high-end, easy to use, Time-Correlated Single Photon Counting (TCSPC) and Multi-Channel Scaling (MCS) board for the PCIe interface. It is based in a custom TDC design that offers an ultrashort dead time even at high temporal resolutions. The board is available in two versions with either 25 ps (PICO module) or 1 ns (NANO module) base resolution. Each version of the TimeHarp 260 is available in different configurations with either one or two independent detection channels and an additional common sync input. The TimeHarp 260 can be used in histogramming mode as well as in a Time-Tagged Time-Resolved (TTTR) that offers an unlimited measurement range at full resolution. A library (DLL) supports custom programming in e.g. C/C++, Delphi, Visual Basic and LabVIEW. |
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PCI-board for Time-Correlated Single Photon Counting |
TimeHarp 200 |
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The TimeHarp 200 PC-board is a complete system for picosecond time-resolved measurements. The board is based on a high throughput PCI bus design. It allows measurement rates up to 3 million counts/sec and provides a time resolution under 40 ps. External hardware such as scanners can be directly connected for synchronization. Interfacing is provided for all common single photon detectors. A library (DLL) supports custom programming in e.g. C/C++, Delphi, Visual Basic and LabVIEW. There is also a 4 channel router for multichannel applications with SPAD or PMT detectors. A Time-Tagged Time-Resolved (TTTR) mode is available for continuously recording events without onboard histogramming straight to disk. |
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PCI-board for Multichannel Scaling or Photon Counting - DISCONTINUED - |
NanoHarp 250 |
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The NanoHarp 250 is a complete system for multichannel scaling/photon counting. The NanoHarp 250 is an ideal instrument for the acquisition of fluorescence or luminescence decays on the nanosecond to second time scale. The board has two base resolutions of 4 ns and 32 ns and up to 262144 time bins are available. This results in a usable time span of up to 2.15 s. A driver library (DLL) supports custom programming in e.g. C/C++, Delphi, Visual Basic and LabVIEW. |
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| Single Photon Sensitive Detectors |
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Hybrid Photomultiplier Detector Assembly |
PMA Hybrid |
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The PMA Hybrid is a compact single photon sensitive detector based on a fast hybrid photomultiplier tube with peltier cooler to reduce the dark count rate. Different photocathodes with different spectral ranges, timing resolution and active area can be incorporated into the PMA Hybrid to meet the user's needs. In contrast to other detector types, the afterpulsing is negligible. This special features makes the PMA Hybrid especially suited for e.g. Fluorescence Correlation Spectroscopy (FCS), where the afterpulsing peak at early lag times often makes analysis of the autocorrelation function problematic. |
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Single Photon Counting Module |
τ-SPAD |
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The τ-SPAD detector module features an extremely high photon detection efficiency of typically 70 % at 670 nm and can be used to detect single photons over the 400 nm to 1100 nm wavelength range. Its low dark counts, good timing resolution and high quantum efficiency make them an ideal detector for single molecule applications, like Fluorescence Correlation Spectroscopy (FCS) or Fluorescence Lifetime Imaging (FLIM).
The τ-SPAD can now be delivered with a FC/PC fiber connector.
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Single Photon Avalanche Diodes |
PDM Series |
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The Single Photon Avalanche Diode (SPAD) modules of the PDM Series are all solid-state instruments from
Micro Photon Devices (MPD) of Bolzano, Italy. They are specifically designed and optimized for time-resolved photon counting applications. The SPADs feature a high quantum efficiency in the VIS spectral range of up to 49 % @ 550 nm and a very fast timing response down to 50 ps, which make them an ideal detector for a wide range of applications including Single Molecule Spectroscopy. The SPADs are available with a diameter of the active area of 20, 50 or 100µm. |
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Photomultiplier Detector Assembly |
PMA Series |
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The PMA detector is a single photon sensitive, fully integrated, fast time response and low noise detector. The PMA integrates a fast Photomultiplier Tube (PMT), a high voltage power supply and a pre-amplifier. The built in pre-amplifier is specially targeted at timing sensitive applications such as Time-Correlated Single Photon Counting (TCSPC). For selected models thermoelectric cooling and automatic overload protection are available as an option.
The blue sensitive PMA 175 is now available and offers a quantum efficiency up to 40 % at 400 nm.
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| Software |
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Fluorescence Lifetime Imaging and Correlation Software - 64 bit version |
SymPhoTime 64 |
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The SymPhoTime 64 software package is an integrated solution for data acquisition and analysis using PicoQuant's time-resolved confocal microscopes, LSM Upgrade kits or TCSPC electronics. The software is designed for a 64 bit operation system and features a clearly structured graphical user interface (GUI), which guides the user through all necessary steps for an individual analysis or measurement process. The SymPhoTime 64 is based on the special Time-Tagged Time-Resolved (TTTR) data format and includes a wide range of analysis procedures ranging from FLIM and FLIM-FRET to FCS, FCCS, FLCS and analysis of fluorescence time traces. An integrated scripting language („STUPSLANG“) even puts the user in a position to freely add new analysis procedures or customize existing ones.
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Fluorescence Lifetime Imaging and Correlation Software - 32 bit version |
SymPhoTime |
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The SymPhoTime software package integrates virtually all algorithms and methods for the analysis of fluorescence dynamics users may require. The software is designed for a 32 bit operation system and is based on the special Time-Tagged Time-Resolved (TTTR) data format from the TimeHarp 200 TCSPC PC board and the TCSPC modules PicoHarp 300 and HydraHarp 400 and allows users to perform an unlimited number of analysis steps without losing track of interdependence and origin of their measurement and analysis data. Derived results can be obtained through a vast set of analysis tools, such as intensity time trace, burst analysis, lifetime histogramming, Fluorescence (Lifetime) Correlation Spectroscopy (FCS/FLCS), Fluorescence Lifetime Imaging (FLIM) and Förster Resonance Energy Transfer (FRET).
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Global Fluorescence Decay Data Analysis Software |
FluoFit |
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The FluoFit program is a multiexponential fluorescence decay fitting software for PCs. It implements an iterative reconvolution of the instrument response and the observed fluorescence decay with nonlinear error minimization based on the Levenberg-Marquardt algorithms. Up to four-exponential decay models or different lifetime distribution models can be fitted to the observed data. IRF and decay background as well as time shift are included as fit parameters. Anisotropy analysis and advanced error analysis with different methods is also possible. Sophisticated import/export/printing functions are included. FluoFit version 4.55 is now available and includes an improved initial parameter estimation for global analysis and allows importing of multiple files. |
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| Quantum Random Number Generator |
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Quantum Random Number Generator |
PQRNG 150 |
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The PQRNG 150 is a new Quantum Random Number Generator (QRNG) based on the quantum randomness of photon arrival times. The stand alone unit offers turn-key usability, provable and long term statistical quality, and bit rates up to 150 Mbits/s. The design creates a new quality in the sense that it offers substantially higher bit rates than previous solutions available to the public.
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| Photon Counting Accessories |
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Dual SPAD Power Supply |
DSN 102 |
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The dual SPAD power supply DSN 102 controls and monitors the operation of either SPCM-AQR(H) SPAD detectors of Perkin Elmer, the PDM SPADs from MPD, the COUNT SPADs from Laser Components or the τ-SPADs from PicoQuant. It can control two modules at the same time and displays the count rate of one selected module. Furthermore, the DSN 1021 provides protection for the SPAD modules against damage caused by overexposure to light by shutting down the power supply for the detectors. |
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Universal 4-Channel Detector Router For PicoHarp 300 |
PHR 800 |
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The PHR 800 is an accessory for the PicoHarp 300 TCSPC unit (from hardware revision 2.0). The modular routing device supports up to 4 detectors of different types. Settings can be adjusted through the software, which includes selection of input polarity and trigger threshold, so that almost any detector signal can be used. Standards supported are TTL and NIM from commonly used SPAD detectors (e.g. the PDM Series). Optional CFD modules also allow to attach PMTs or MCP-PMTs. The router permits to operate the detectors quasi in parallel on one PicoHarp 300 unit, allowing users to collect fluorescence lifetime decays on multiple channels simultaneously e.g. for polarization anisotropy or multi-colour measurements. |
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Further Accessories |
Accessories |
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Please check our range of further accessories suitable for photon counting applications, high speed timing and similar techniques. These applications require high quality components with proper impedance matching and shielding. The list includes the TDA 200 trigger diode to synchronize photon counting instrumentation with external lasers, the PAM 102 pre-amplifier modules for PMTs and MCPs as well as signal inverters, splitter, attenuators, cables and other related products. |
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